Comparing Galliprant and Gabapentin for Canine Treatment

Galliprant and Gabapentin are common medications prescribed to dogs for the management of pain, anxiety, and seizures. Each drug targets specific aspects of your dog’s symptoms, and the choice between them depends on your dog’s particular needs. The dosage can be tailored to your dog’s requirements, and it’s important to be aware of potential side effects, including lethargy, diarrhea, and incoordination. Consulting your veterinarian is crucial in determining which medication is most suitable for your dog.

Galliprant and Gabapentin are both prescription medications for dogs. Galliprant is effective in managing chronic pain and inflammation, while Gabapentin can help treat seizures, pain, and anxiety. Your veterinarian will assess your dog’s specific symptoms and determine the appropriate medication and dosage.

What Is Galliprant?

Galliprant, also known as grapiprant, is a non-steroidal anti-inflammatory drug (NSAID) prescribed to alleviate chronic pain associated with conditions like osteoarthritis and hip dysplasia in dogs. This medication effectively addresses chronic pain while minimizing strain on the kidneys, liver, and gastrointestinal system. Galliprant is available in pork or liver-flavored tablets or capsules, making it palatable for dogs. It is safe for dogs as young as one year old and older. The dosage is determined by a qualified veterinarian.


Galliprant is primarily used to manage pain and inflammation resulting from canine osteoarthritis. It is safe for daily use in dogs weighing over 8 pounds. The chewable tablet is administered once a day, and it helps relieve joint-related pain without adverse effects on the liver, kidneys, or gastrointestinal system.

Side Effects

Common side effects of Galliprant include vomiting, diarrhea, reduced appetite, and lethargy. While these side effects typically resolve on their own, they may occasionally require veterinary attention. Kidney or liver damage is a rare but serious side effect, and Galliprant may interact with other medications. Always inform your veterinarian about other medications your dog is taking and seek professional advice if side effects persist or worsen.


Galliprant is available in tablet form, with dosages of 20 mg, 60 mg, and 100 mg. The appropriate dose for your dog will be determined by your veterinarian, considering factors like breed, weight, and specific symptoms. It is essential to note that Galliprant is not suitable for dogs under 8 lbs., as accurate dosing is challenging. Typically, veterinarians recommend starting with the lowest possible dose and adjusting it as necessary.

What Is Gabapentin?

Gabapentin is classified as an anticonvulsant medication designed to treat seizures but has also shown effectiveness in relieving anxiety and chronic pain related to nerve damage, such as arthritis. Although originally developed for humans, Gabapentin is often prescribed for dogs due to their positive response. The medication works by modifying neurotransmitter activity in the brain, reducing the nervous system’s reaction to specific stimuli.


Gabapentin is a fast-acting medication effective in treating anxiety, seizures, and chronic pain in dogs. It is commonly prescribed to alleviate chronic pain resulting from nerve damage, such as canine arthritis or cancer, manage anxiety, and reduce epileptic seizures. As a painkiller, Gabapentin blocks neurons stimulated during pain perception, providing relief to dogs suffering from chronic joint pain.

Side Effects

Dogs generally respond well to Gabapentin, with minimal to no side effects. Possible side effects may include drowsiness, vomiting, diarrhea, and coordination issues. While these side effects are usually not severe, they may indicate the need for a dosage adjustment. It is advisable to consult your veterinarian if your dog experiences significant drowsiness or coordination problems. Fortunately, these side effects are temporary and tend to diminish within 24 hours.


Gabapentin should always be prescribed by a licensed veterinarian, who will determine the most suitable dose for your dog. The typical dosage is approximately 5 mg per kg of body weight every 12 hours, with adjustments based on individual factors like breed, weight, and preexisting conditions.

Comparing Galliprant Vs. Gabapentin

Both medications offer pain relief, but they have different mechanisms of action and applications. Galliprant is an NSAID, similar to ibuprofen, effective primarily as a painkiller. In contrast, Gabapentin acts on the brain’s neurotransmitters, making it suitable for managing seizures, neurological issues, and anxiety. Both medications are available in tablet form, with flavors to enhance palatability.

Which Medication Is Right For Your Dog?

The choice between Galliprant and Gabapentin depends on your dog’s specific symptoms. Galliprant is particularly effective for arthritic pain, while Gabapentin is suitable for managing seizures, anxiety, and nerve-related chronic pain. Consult your veterinarian to determine the most appropriate treatment based on your dog’s breed, size, overall health, and any preexisting conditions. Always use these medications under veterinary supervision, as they may not be suitable for dogs with kidney or liver issues, as well as pregnant or nursing dogs.

Final Notes

Both Galliprant and Gabapentin offer effective solutions for managing your dog’s pain, anxiety, or seizures. Their distinct mechanisms of action make them more suitable for specific symptoms. To make an informed choice, consult with a licensed veterinarian to ensure the well-being of your beloved canine companion.