Deramaxx in Dogs: Applications, Dosage, and Adverse Effects

As a devoted dog owner, witnessing your canine companion in distress can evoke a sense of helplessness and concern. Dogs bring immeasurable joy and fulfillment to our lives, making it particularly challenging when they are unwell or in pain. In such situations, a visit to the veterinarian may result in a prescription for a medication that may be unfamiliar to you. In this comprehensive article, we will provide you with essential information about Deramaxx, one of the commonly prescribed pain medications for dogs.

What Is Deramaxx?

Deramaxx is a non-narcotic, non-steroidal anti-inflammatory drug designed exclusively for dogs, belonging to the broader category of medications known as NSAIDs. These medications are versatile in addressing various conditions, and they are generally well-tolerated by most dogs. The key advantage of NSAID medications is their ability to swiftly alleviate pain and inflammation while typically causing fewer long-term side effects than steroid drugs.

Deramaxx is available in the form of chewable tablets and is intended exclusively for canine use. It is not suitable for cats, humans, or other animals and must only be administered to dogs with a valid prescription from a licensed veterinarian. These chewable tablets contain deracoxib, a component that effectively reduces pain, fever, and inflammation. Furthermore, the tablets are formulated with a palatable beef-like flavor, making them more readily accepted by dogs and providing rapid pain relief.


Deramaxx, like other NSAIDs, is primarily employed to alleviate pain and reduce inflammation associated with chronic conditions, including arthritis, as well as for pain management following surgical procedures. It serves a similar role in dogs as Ibuprofen does in humans. Deramaxx is a fast-acting and relatively straightforward pain reliever that can effectively improve your dog’s comfort in various circumstances. Its chewable format and appealing flavor make it a convenient choice for canine medication.

One of the primary applications of Deramaxx is in the treatment of osteoarthritis in dogs. Osteoarthritis is the most prevalent form of arthritis in dogs, affecting approximately 14 million canines in the United States. This condition is characterized by cartilage loss, joint thickening, and the formation of new bone around affected joints, resulting in chronic pain and potential limb dysfunction. Osteoarthritis often develops as a secondary consequence of primary conditions, such as hip dysplasia, knee cap dislocation, or ligament disease. It can affect dogs at any stage of their lives, with older, larger, and overweight dogs at a higher risk. Other contributing factors include athletic activities, poor nutrition, genetics, injuries, and joint-related infections.

Side Effects

While Deramaxx is generally well-tolerated by most dogs, some may experience adverse side effects, which can include:

  1. Allergic reactions (itching, swelling, hives, difficulty breathing)
  2. Vomiting
  3. Diarrhea
  4. Abdominal pain
  5. Seizures
  6. Lethargy
  7. Stomach ulcers
  8. Altered urination and thirst patterns (resulting from reduced kidney function)
  9. Balance or coordination issues

These side effects are more likely to occur in dogs with preexisting conditions and are relatively uncommon in young and healthy dogs. Additionally, a dog’s breed can significantly influence their response to NSAIDs like Deramaxx. If your dog exhibits any side effects from medication, it is crucial to consult with your veterinarian.


The prescription and administration of Deramaxx should be solely determined by a licensed veterinarian. Veterinarians are well-equipped to determine the appropriate dosage based on your dog’s breed, size, and specific condition. Typically, the initial prescription will start with a minimal dose to assess your dog’s response.

The standard recommended daily dosage ranges from 0.45mg/lb to 0.91mg/lb and should be administered orally. Deramaxx is available in 12 mg, 25 mg, 75 mg, and 100 mg tablet forms, with 25 mg tablets being the most common for medium-sized dogs. Smaller dogs may require a smaller dosage, while larger dogs may need a higher dose.


What is osteoarthritis? Osteoarthritis is the most prevalent type of arthritis in dogs. It affects the joints, causing chronic pain, stiffness, and, in some cases, difficulty with limb functionality. Symptoms of osteoarthritis may include limping, pain, reduced activity, an inability to jump, and alterations in gait. Older, larger, and overweight dogs are at a higher risk of developing osteoarthritis, as are dogs with preexisting conditions affecting the joints or muscles.

Does Deramaxx induce drowsiness in dogs? Deramaxx is not typically associated with drowsiness in dogs, although they may exhibit some lethargy and reduced energy levels. If you notice excessive drowsiness in your dog following Deramaxx administration, it is advisable to contact your veterinarian or seek emergency veterinary care.

Can cats take Deramaxx? No, Deramaxx is exclusively intended for use in dogs and should not be administered to cats, humans, or other animals. There are alternative treatments available for cats with osteoarthritis, including cat-safe NSAID drugs, dietary supplements, physical rehabilitation, or surgery.

Final Notes

Deramaxx has been a trusted and effective canine medication for many years. It offers efficient pain relief, addressing chronic pain resulting from osteoarthritis, as well as post-operative pain, similar to the way humans use Ibuprofen.

In most cases, dogs respond positively to Deramaxx; however, exceptions do exist. As with any medication, side effects may occur, especially in dogs with preexisting conditions or small dogs requiring lower doses. It is crucial to remember that Deramaxx is not suitable for use in humans, cats, or other animals and should only be administered to your dog under the guidance and prescription of your veterinarian.

For a comprehensive evaluation of your dog’s pain level and to determine if Deramaxx is an appropriate treatment, our licensed veterinarians at Dutch can provide valuable guidance. Receive expert advice regarding Deramaxx and explore tailored treatment plans for your dog, all from the comfort of your own home through our pet telemedicine platform.