The extremely positive results supported a diagnosis of lepromatous leprosy. This form of leprosy characterized by an ineffective immune response is anergic. Infection of the nerves is associated with the gradual development of nerve injury. Five months of multidrug therapy with the addition of prednisone were administered to the patient. After nine months of multidrug treatment, the left eyelid’s skin infiltration and frailty had diminished (Panel B). The standard treatment duration for multibacillary leprosy is 12 months, whereas anergic polar forms, such as those observed in this patient, typically require 24 months of treatment to achieve a cure.